Tell her to get out and stay out.
That depends on your attitude toward the cow. If you like having a cow in your house, you could try giving it a name and feeding it grass. If, on the other hand, you don't want a cow in your house, you could gently guide it outside and remember to close the door more carefully in the future. If you aren't sure, you could keep the cow around for a few days and find out whether small-scale animal husbandry is a good match for your lifestyle and decor.
lol. try calling animal control.
Have a barbecue.
Better not let your wife hear you call her that.
Milk it !!